Researcher Directory | Osaka City University


NAGASAKI Takeshi

  • Department:Graduate School of Engineering Applied Chemistry and Bioengineering (Applied Chemistry and Bioengineering) Position:Professor
Last Updated:2017/01/27

Career

Professional Career

  • 1991-1994 Faculty of Engineering, Kyushu University

Research Achievements

Books・Papers

  • HVJ-E/importin-b hybrid vector for overcoming cytoplasmic and nuclear membranes as double barrier for non-viral gene delivery
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2012/07
    Name of Publisher/Name of Journal:Elsevier
    Volume/Number,Page:66(7):519-524
    Authors:Takeshi Kawazu, Hiroyuki Kanzaki, Atsushi Uno, Hideki Azuma, Takeshi Nagasaki
  • Photochemical controlof membrane raft organization
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2011
    Name of Publisher/Name of Journal:Soft Matter
    Volume/Number,Page:7:220-224
    Authors:T. Hamada, R. Sugimoto, T. Nagasaki, M. Takagi
  • Anti-inflammatory effect of water-soluble complex of 1’-acetoxychavicol acetate with highly branched -1,3-glucan on contact dermatitis
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2015/02
    Name of Publisher/Name of Journal:Biomed. Biopharmacother.
    Volume/Number,Page:69:201-207
    Authors:Jiawei Li , Yui Aizawa, Keiichi Hiramoto, Emiko Kasahara, Daisuke Tsuruta, Toshio Suzuki, Atsushi Ikeda, Hideki Azuma
  • Evaluation of Biocompatible Polylysine Bearing BSH as a Polymeric Agent for Boron Neutron Capture Therapy
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2014/10
    Name of Publisher/Name of Journal:KURRI Progress Report 2013
    Volume/Number,Page::281
    Authors:R. Kawasaki, M. Sakuramoto, M. Kirihata, K. Ono, S. Masunaga, Y. Sakurai
    ISSN:0919-1038
  • Hypoxia-induced Factor (HIF)-1α Inhibition and Metastasis Suppression with BNCT by Using Kojic Acid Modified o-Carborane
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2014/10
    Name of Publisher/Name of Journal:KURRI Progress Report 2013
    Volume/Number,Page::124
    Authors:R. Kawasaki, M. Sakuramoto, S. Iizuka, M. Kirihata, Y. Hattori, S. Masunaga,Y. Sakurai
    ISSN:0919-1038
  • Tumor growth suppression by gadolinium-neutron capture therapy using gadolinium-entrapped liposome as gadolinium delivery agent
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2013
    Name of Publisher/Name of Journal:Biomed. Biopharmacother.
    Volume/Number,Page:67:451-457
    Authors:Novriana Dewi, Hironobu Yanagie, Masaki Sekino, Takeshi Nagasaki et al.
  • Mechanism Involved in Tumor Tissue of Colon 26 Carcinoma - Bearing Mice Irradiated with Neutron in the Presence of BSH - Appended Polyamine
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2013
    Name of Publisher/Name of Journal:KURRI Progress Report 2012
    Volume/Number,Page::CO6
    Authors:Takeshi Nagasaki, Riku Kawasaki , Masashi Sakuramoto, Hideki Azuma, et al.
  • Kojic Acid - Appended Carorane/Hydroxypropyl-beta- Cyclodextrin Complex for BNCT of Murine Melanoma
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2013
    Name of Publisher/Name of Journal:KURRI Progress Report
    Volume/Number,Page::PR6-6
    Authors:Riku Kawasaki, Takeshi Nagasaki , Jiawei Li , Hideki Azuma et al.
  • Intracellular Distribution of BSH-Appended Polyamine at Tumor Tissue of Colon 26 Carcinoma-Bearing Mice
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2012
    Name of Publisher/Name of Journal:KURRI Progress Report 2011
  • Kojic Acid-Appended Carorane/Hydroxypropyl-beta-Cyclodextrin Complex: A Novel Boron Carrier for Melanoma Targeting
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2012
    Name of Publisher/Name of Journal:KURRI Progress Report 2011
Display all
Books・Papersclose
  • HVJ-E/importin-b hybrid vector for overcoming cytoplasmic and nuclear membranes as double barrier for non-viral gene delivery
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2012/07
    Name of Publisher/Name of Journal:Elsevier
    Volume/Number,Page:66(7):519-524
    Authors:Takeshi Kawazu, Hiroyuki Kanzaki, Atsushi Uno, Hideki Azuma, Takeshi Nagasaki
  • Photochemical controlof membrane raft organization
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2011
    Name of Publisher/Name of Journal:Soft Matter
    Volume/Number,Page:7:220-224
    Authors:T. Hamada, R. Sugimoto, T. Nagasaki, M. Takagi
  • Anti-inflammatory effect of water-soluble complex of 1’-acetoxychavicol acetate with highly branched -1,3-glucan on contact dermatitis
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2015/02
    Name of Publisher/Name of Journal:Biomed. Biopharmacother.
    Volume/Number,Page:69:201-207
    Authors:Jiawei Li , Yui Aizawa, Keiichi Hiramoto, Emiko Kasahara, Daisuke Tsuruta, Toshio Suzuki, Atsushi Ikeda, Hideki Azuma
  • Evaluation of Biocompatible Polylysine Bearing BSH as a Polymeric Agent for Boron Neutron Capture Therapy
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2014/10
    Name of Publisher/Name of Journal:KURRI Progress Report 2013
    Volume/Number,Page::281
    Authors:R. Kawasaki, M. Sakuramoto, M. Kirihata, K. Ono, S. Masunaga, Y. Sakurai
    ISSN:0919-1038
  • Hypoxia-induced Factor (HIF)-1α Inhibition and Metastasis Suppression with BNCT by Using Kojic Acid Modified o-Carborane
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2014/10
    Name of Publisher/Name of Journal:KURRI Progress Report 2013
    Volume/Number,Page::124
    Authors:R. Kawasaki, M. Sakuramoto, S. Iizuka, M. Kirihata, Y. Hattori, S. Masunaga,Y. Sakurai
    ISSN:0919-1038
  • Tumor growth suppression by gadolinium-neutron capture therapy using gadolinium-entrapped liposome as gadolinium delivery agent
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2013
    Name of Publisher/Name of Journal:Biomed. Biopharmacother.
    Volume/Number,Page:67:451-457
    Authors:Novriana Dewi, Hironobu Yanagie, Masaki Sekino, Takeshi Nagasaki et al.
  • Mechanism Involved in Tumor Tissue of Colon 26 Carcinoma - Bearing Mice Irradiated with Neutron in the Presence of BSH - Appended Polyamine
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2013
    Name of Publisher/Name of Journal:KURRI Progress Report 2012
    Volume/Number,Page::CO6
    Authors:Takeshi Nagasaki, Riku Kawasaki , Masashi Sakuramoto, Hideki Azuma, et al.
  • Kojic Acid - Appended Carorane/Hydroxypropyl-beta- Cyclodextrin Complex for BNCT of Murine Melanoma
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2013
    Name of Publisher/Name of Journal:KURRI Progress Report
    Volume/Number,Page::PR6-6
    Authors:Riku Kawasaki, Takeshi Nagasaki , Jiawei Li , Hideki Azuma et al.
  • Intracellular Distribution of BSH-Appended Polyamine at Tumor Tissue of Colon 26 Carcinoma-Bearing Mice
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2012
    Name of Publisher/Name of Journal:KURRI Progress Report 2011
  • Kojic Acid-Appended Carorane/Hydroxypropyl-beta-Cyclodextrin Complex: A Novel Boron Carrier for Melanoma Targeting
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2012
    Name of Publisher/Name of Journal:KURRI Progress Report 2011
  • Quantitative comparison between poly(L-arginine) and poly(L-lysine) at each step of polyplex-based gene transfection using a microinjection technique
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2012/03
    Name of Publisher/Name of Journal:Sci. Technol. Adv. Mater.
    Volume/Number,Page:13(1)
    Authors:Tomoko Hashimoto, Takeshi Kawazu, Takeshi Nagasaki, Akira, Murakami, Tetsuji Yamaoka
  • Protein Recognition of Hetero-/Homoleptic Ruthenium(II) Tris(bipyridine)s for -Chymotrypsin and Cytochrome c
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2012/03
    Name of Publisher/Name of Journal:Bioorg. Med. Chem. Lett.
    Volume/Number,Page:22(6):2354-2358
    Authors:Yoshinobu Yamaguchi, Nobuo Kato, Hideki Azuma, Takeshi Nagasaki and Junko Ohkanda
  • Lateral phase separation in tense membranes
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2011/10
    Name of Publisher/Name of Journal:Soft Matter
    Volume/Number,Page:7(19):9061-9068
    Authors:Tsutomu Hamada, Yuko Kishimoto, Takeshi Nagasaki and Masahiro Takagi
  • Biological activity of water-soluble inclusion complexes of 1′-acetoxychavicol acetate with cyclodextrins
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2011/06
    Name of Publisher/Name of Journal:Bioorg. Med. Chem.
    Volume/Number,Page:19(12):3855-3863
    Authors:Hideki Azuma, Yui Aizawa, Nao Higashitani, Takashi Tsumori, Akiko Kojima-Yuasa, Isao Matsui-Yuasa and Takeshi Nagasaki
  • Tumor Accumulation of e-Poly-Lysines-Based Polyamines Conjugated with Boron Clusters
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2011/12
    Name of Publisher/Name of Journal:Applied Radiation and Isotopes
    Volume/Number,Page:69(12):1765-1767
    Authors:Masayuki Umano, Kazuhiro Uechi, Takatoshi Uriuda, Sayuri Murayama, Hideki Azuma, Takeshi Nagasaki et al.
  • Ultrasound-mediated Transfection with Liposomal Bubbles Delivers Plasmid DNA Directly into Nucleu
    Type:Book
    by Single Author or Co-authored:Co-authored
    Date of Publication:2011/03
    Name of Publisher/Name of Journal:Chem. Lett.
    Authors:Takeshi Kawazu, Kazumi Hakamada, Yusuke Oda, Jun Miyake, Kazuo Maruyama, and Takeshi Nagasaki
  • Membrane disc and sphere:controllable mesoscopic structures for the capture
    and release of a targeted object
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2010
    Name of Publisher/Name of Journal:J. Am. Chem. Soc.
    Volume/Number,Page:132:10528-10532
    Authors:T. Hamada, R. Sugimoto, M.C. Vestergaard, T. Nagasaki, M. Takagi
  • Enhanced internalization and endosomal escape of dual-functionalized poly(ethyleneimine)s polyplex with Diphtheria Toxin T and R domains
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2010
    Name of Publisher/Name of Journal:Biomed. Biopharmacother.
    Volume/Number,Page:64(4):296-301
    Authors:S. Kakimoto, T. Tanabe, H. Azuma, T. Nagasaki
  • Self-Assembly and Cellular Uptake of Degradable and Water-Soluble Polyperoxides
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2009
    Name of Publisher/Name of Journal:Bioconjug. Chem.
    Volume/Number,Page:20(10):1879-1887
    Authors:Tamami Fujioka, Shuji Taketani, Takeshi Nagasaki and Akikazu Matsumoto
  • Target-selective vesicle fusion system with pH-selectivity and responsiveness
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2009
    Name of Publisher/Name of Journal:Soft Matter
    Volume/Number,Page:5:4719-4725
    Authors:Ayumi Kashiwada, Mana Tsuboi, Toshihisa Mizuno, Takeshi Nagasaki and Kiyomi Matsuda
  • Cytochrome c-bionding"proteo-dendrimers" as new types of apoptosis
    inhibitors working in HeLa cell systems
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2009
    Name of Publisher/Name of Journal:Org. Biomol. Chem.
    Volume/Number,Page:7:1700-1704
    Authors:Hideki Azuma, Yuuka Yoshida, Dharam Paul, Satoshi Shinoda, Hiroshi Tsukube, Takeshi Nagasaki
  • Reversible Controlof Exo- and Endo-BuddingTransitions in a Photosensitive
    Lipid Membrane.
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2009
    Name of Publisher/Name of Journal:ChemBioChem
    Volume/Number,Page:10(2):251-256
    Authors:K. Ishii,T. Hamada, M. Hatakeyama, R. Sugimoto, T. Nagasaki, M. Takagi
  • The conjugation ofdiphtheria toxin T domain to poly(ethylenimine)based vectors for enhanced endosomal escape during gene transfection.
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2009
    Name of Publisher/Name of Journal:Biomaterials
    Volume/Number,Page:30(3):402-408
    Authors:S. Kakimoto, T. Hamada, Y. Komatsu, M. Takagi, T. Tanabe, H. Azuma, S. Shinkai, T. Nagasaki
  • Intracellular uptake and photodynamic activity of water-soluble [60]and
    [70]fullerenes incorporated in liposomes.
    Type:Paper
    by Single Author or Co-authored:Single Author
    Date of Publication:2008
    Name of Publisher/Name of Journal:Chem. Eur. J.
    Volume/Number,Page:14(29):8892-8897
  • Isothiouronium-based amphiphilic gold nanoparticles with a colorimetric response to hydrophobic anions in water: a new strategy for fluoride ion detection in the presence of a phenylboronic acid
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2008
    Name of Publisher/Name of Journal:Tetrahedron Lett.
    Volume/Number,Page:49(3):432-436
    Authors:Tsuyoshi Minami, Kenji Kaneko, Takeshi Nagasaki and Yuji Kubo
  • Dual-ligand effect of transferrin and transforming growth factor alpha on polyethyleneimine-mediated gene delivery.
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2007
    Name of Publisher/Name of Journal:J. Control. Release
    Volume/Number,Page:120(3):242-249
    Authors:S. Kakimoto, T. Moriyama, T. Tanabe, S. Shinkai, and T. Nagasaki
  • In vitro gene delivery HepG2 cells using a galactosylated 6-amino-6-deoxychitosan as a DNA carrier.
    Type:Paper
    by Single Author or Co-authored:Co-authored
    Date of Publication:2007
    Name of Publisher/Name of Journal:Carbohydr. Res.
    Volume/Number,Page:342(11):1427-1433
    Authors:T. Satoh, S. Kakimoto, H. Kano, M. Nakatani, S. Shinkai, and T. Nagasaki

Research Funds

Grants-in-Aid for Scientific Research

  • Research Title:Development of Inorganic Boron Cluster-fused Delivery Materials for the Neutron Capture Therapy
    Principal Investigator or Co-Investigator:Principal Investigator
    Year of Application:2011
    Project Year:2011/04~2013/03
    Budget Amount 【Direct】:
    1st Year 2300(thousand Yen)
    2nd Year 2300(thousand Yen)
    Budget Amount 【Indirect】:
    1st Year 690(thousand Yen)
    2nd Year 690(thousand Yen)
  • Research Title:Study on interaction between the photoresponsive dendrimer and biorelative compounds
    Principal Investigator or Co-Investigator:Principal Investigator
    Year of Application:1997
    Project Year:1997/04~2000/03
    Budget Amount 【Direct】:
    1st Year 2500(thousand Yen)
    2nd Year 600(thousand Yen)
    3rd Year 500(thousand Yen)
    Budget Amount 【Indirect】:
    1st Year 0(thousand Yen)
    2nd Year 0(thousand Yen)
    3rd Year 0(thousand Yen)

Industrial-Academic-Government Cooperation

Research Department

  • Graduate School of Engineering Applied Chemistry and Bioengineering (Applied Chemistry and Bioengineering)

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